Aprimary goal of the meeting is to provide a symposium where medical scientists from academia can interact with clinician and scientists from the biopharmaceutical industry, thus forging a community of academic and industry researchers who recognize that they have much to learn from each other. Rational drug discovery for neurodegenerative diseases has begun to yield compounds and treatments that are now entering clinical settings. For human studies utilizing these compounds and treatments to be maximally informative, it is crucial that scientists from academia clinician and industry meet regularly to exchange data and ideas.！